The national study was led by the John James Medical Center and the Murdoch Children’s Research Institute (MCRI) and published in the Journal of Allergy and Clinical Immunology. It examined a total of 37,132 food anaphylaxis hospital admissions via national emergency department data across the three time periods of 1998-1999 to 2006-2007, 2007-2008 to 2014-2015, and 2015-2016 to 2018-2019, based on several age groups.

Researchers aimed to examine the impacts of implementing allergy prevention guidelines on a national (implemented in 2007-2008) and global (implemented in 2015-2016), particularly to determine whether these had resulted in any parallel reductions in hospital admissions due to food anaphylaxis.

One of the major guideline changes highlighted was that of introducing allergens to infant diets before the age of one, before the child develops the allergy, in order to prevent this from developing – this was because the results showed a slowing in food anaphylaxis rates amongst children aged between one and 14 years of age.

“The results [for these age groups] coincide with the introduction of updated infant feeding and allergy prevention guidelines in 2007-2008 and 2015-2016, “MCRI Professor Mimi Tang said.

“This Study is the first real-world evidence to show that updates to allergy prevention and infant feeding guidelines are having a measurable impact on the population prevalence of food anaphylaxis. “..

Children in the one to four-year-old age group showed a 13.7% slow in annual anaphylaxis rates of increase across the three time periods from 17.6% to 6.2% to 3.9%; those in the five to nine-year-old group dropped even more by 24.4% from 22% to 13.9% to –2.4%; and those in the 10 to 14-year-old group dropped 6.7% overall from 17.5% to 18.0% to 10.8%.


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